Case Study The British journal of oral & maxillofacial surgery 2001

Acne with chronic recurrent multifocal osteomyelitis involving the mandible as part of the SAPHO syndrome: case report.

Roldán JC, Terheyden H, Dunsche A, Kampen WU, Schroeder JO — The British journal of oral & maxillofacial surgery, 2001

View Original on PubMed PMID 11286450

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described the case of a 26-year-old man diagnosed with SAPHO syndrome, detailing his symptoms and treatment course over 12 years.

What They Found

They found that a 26-year-old man suffered from acne conglobata and chronic recurrent multifocal osteomyelitis for 12 years, fulfilling SAPHO syndrome criteria. While initial treatments provided partial improvement, complete relief and partial disappearance of lesions were achieved with long-term corticosteroids, NSAIDs, minocycline, and isotretinoin.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a case report, the findings are limited to a single patient and cannot be generalized to a broader population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Study
Category	Infection
Source	Pubmed
PubMed ID	11286450
Year Published	2001
Journal	The British journal of oral & maxillofacial surgery
MeSH Terms	Acne Vulgaris; Acquired Hyperostosis Syndrome; Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Inflammatory Agents; Dermatologic Agents; Drug Therapy, Combination; Humans; Isotretinoin; Male; Mandibular Diseases; Osteomyelitis; Prednisolone; Radionuclide Imaging

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology