Addition of hyperbaric oxygen therapy versus usual care alone for inflammatory bowel disease: A systematic review and meta-analysis | Canada Hyperbarics Skip to main content
Meta-Analysis Heliyon 2022

Addition of hyperbaric oxygen therapy versus usual care alone for inflammatory bowel disease: A systematic review and meta-analysis

You J, Jiang J, He W, Ma H, Zhou M, Chen X, et al. — Heliyon, 2022

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review and meta-analysis to determine if adding hyperbaric oxygen therapy (HBOT) to usual care helps treat inflammatory bowel disease (IBD) and reduces its recurrence rate.

What They Found

This review included 29 studies with 2151 patients, primarily with ulcerative colitis (UC). For UC patients, adding HBOT to usual care increased the likelihood of a clinical response by 24% (risk ratio 1.24) compared to usual care alone. HBOT also reduced the recurrence rate of IBD by 65% (risk ratio 0.35), and no severe adverse events were observed.

What This Means for Canadian Patients

If these findings are confirmed, Canadian patients with IBD, particularly UC, might benefit from HBOT as an additional treatment to improve their condition and prevent flare-ups. This could offer a new option for managing a chronic and often debilitating disease.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The study was limited by the lack of randomized data for Crohn's disease and the varied nature of the included studies, which required a random-effects model.

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Study Details

Study Type Meta-Analysis
Category Wound Care
Source Pubmed
PubMed ID 36276722
Year Published 2022
Journal Heliyon

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.