Adjunctive hyperbaric oxygen therapy in the management of severe lower limb soft tissue injuries: a systematic review | Canada Hyperbarics Skip to main content
Systematic Review Eur J Trauma Emerg Surg 2024

Adjunctive hyperbaric oxygen therapy in the management of severe lower limb soft tissue injuries: a systematic review

Kwee E, Borgdorff M, Schepers T, Halm J, Winters H, Weenink R, et al. — Eur J Trauma Emerg Surg, 2024

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Dutch researchers systematically reviewed seven studies (229 patients total) examining whether adding HBOT to standard trauma care improved outcomes in patients with severe crush injuries and soft tissue damage to the lower limbs.

What They Found

A randomized placebo-controlled trial within the review showed HBOT significantly increased wound healing and reduced the need for additional surgery compared to sham treatment. A second randomized trial found that early HBOT reduced tissue death and long-term complications. A retrospective cohort study showed HBOT reduced infection rates and repeat surgeries. Case reports and series also showed positive healing results.

What This Means for Canadian Patients

For Canadians who suffer severe leg crush injuries, from accidents, industrial incidents, or falls, adding HBOT to surgical care may mean faster healing, fewer infections, and a lower chance of needing additional operations. Trauma centers with hyperbaric access may be better positioned to manage these complex cases.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

Only seven studies with 229 patients were available, with mixed study designs and varying HBOT protocols, making it difficult to define optimal treatment timing and dosing.

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Study Details

Study Type Systematic Review
Category Wound Care
Source Pubmed
PubMed ID 38386077
Year Published 2024
Journal Eur J Trauma Emerg Surg
MeSH Terms Hyperbaric Oxygenation; Humans; Soft Tissue Injuries; Wound Healing; Crush Injuries; Leg Injuries; Lower Extremity

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.