An assessment of the efficacy of stress-protector pharmacological preparations and hyperbaric oxygenation in patients in the perioperative period | Canada Hyperbarics Skip to main content
RCT Anesteziol Reanimatol 2000

An assessment of the efficacy of stress-protector pharmacological preparations and hyperbaric oxygenation in patients in the perioperative period

Kiriachkov I, Khmelevskiĭ I, Sloventantor V, Vorontsova E — Anesteziol Reanimatol, 2000

View Original on PubMed PMID 10900712
Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers investigated how certain medications and hyperbaric oxygen therapy (HBOT) affected the body's stress response in 74 surgical patients.

What They Found

The study found that all tested drugs (propranolol, cordanum, clonidine, dalargin) and HBOT modulated the body's adaptation response. HBOT involved 100% oxygen for 1 hour at 1.5 ATA. These interventions also led to improved outcomes for patients undergoing surgery.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study was conducted over two decades ago, and the abstract provides limited detail on the specific measures of "improved outcomes" or long-term follow-up.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type RCT
Category Cardiac
Source Pubmed
PubMed ID 10900712
Year Published 2000
Journal Anesteziol Reanimatol
MeSH Terms Adaptation, Physiological; Algorithms; Female; Hemodynamics; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Nervous System; Perioperative Care; Stress, Physiological; Time Factors

Cite This Study

Share

Related Research

Cardiology | 1998 RCT

Hyperbaric oxygen and thrombolysis in myocardial infarction: the ‘HOT MI’ randomized multicenter study

Stavitsky Y, Shandling AH, Ellestad MH, et al.
Cardiovasc Revasc Med | 2020 RCT

Hyperbaric oxygen therapy following percutaneous coronary intervention for ST-segment elevation myocardial infarction

Martin-Hernandez P, Palacios P, Rodriguez-Bobada C, et al.
J Physiol Anthropol | 2025 RCT

A study on the effect of acute hyperbaric oxygen intervention on aerobic endurance

Hu Z, Guo W, Wu H
Cochrane Database Syst Rev | 2015 Systematic Review

Hyperbaric oxygen therapy for acute coronary syndrome

Bennett M, Lehm J, Jepson N
J Cardiothorac Vasc Anesth | 2011 RCT

Preconditioning with repeated hyperbaric oxygen induces myocardial and cerebral protection in patients undergoing coronary artery bypass graft surgery: a prospective, randomized, controlled clinical trial

Li Y, Dong H, Chen M, Liu J, Yang L, Chen S, et al.
See all Cardiac research
View on PubMed Back to Research Library

Find a Canadian Clinic

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology