RCT Anesteziol Reanimatol 2000

[An assessment of the efficacy of stress-protector pharmacological preparations and hyperbaric oxygenation in patients in the perioperative period]

Kiriachkov I, Khmelevskiĭ I, Sloventantor V, Vorontsova E — Anesteziol Reanimatol, 2000

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers investigated how certain medications and hyperbaric oxygen therapy (HBOT) affected the body's stress response in 74 surgical patients.

What They Found

The study found that all tested drugs (propranolol, cordanum, clonidine, dalargin) and HBOT modulated the body's adaptation response. HBOT involved 100% oxygen for 1 hour at 1.5 ATA. These interventions also led to improved outcomes for patients undergoing surgery.

What This Means for Canadian Patients

This research suggests that HBOT, when used alongside specific medications, could potentially help Canadian patients manage the stress associated with surgery. By regulating the body's response to surgical procedures, these treatments might contribute to better recovery and overall outcomes after operations.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study was conducted over two decades ago, and the abstract provides limited detail on the specific measures of "improved outcomes" or long-term follow-up.

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Study Details

Study Type	RCT
Category	Cardiac
Source	Pubmed
PubMed ID	10900712
Year Published	2000
Journal	Anesteziol Reanimatol
MeSH Terms	Adaptation, Physiological; Algorithms; Female; Hemodynamics; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Nervous System; Perioperative Care; Stress, Physiological; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.