Antibiotic utilization in hospitalized children under 2 years of age with influenza or respiratory syncytial virus infection - a comparative, retrospective analysis | Canada Hyperbarics Skip to main content
Retrospective Study BMC Infect Dis 2020

Antibiotic utilization in hospitalized children under 2 years of age with influenza or respiratory syncytial virus infection - a comparative, retrospective analysis

Papan C, Willersinn M, Weiß C, Karremann M, Schroten H, Tenenbaum T — BMC Infect Dis, 2020

View Original on PubMed PMID 32807104
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a retrospective study at a single hospital to compare antibiotic use in children under two years old hospitalized with either Respiratory Syncytial Virus (RSV) or influenza (FLU) infections.

What They Found

Out of 573 hospitalized children, 476 (83.1%) had RSV and 95 (16.6%) had FLU. Children with RSV had longer hospital stays (median 5 days vs. 4 days) and needed oxygen more frequently (314/476 vs. 23/95). The overall rate of antibiotic use was comparable between RSV (136/476) and FLU (21/95) patients. Factors significantly associated with antibiotic use included a septic appearance on admission (odds ratio 8.95), acute otitis media (OR 4.5), longer oxygen therapy (OR 1.40), and a higher C-reactive protein (OR 1.7).

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This was a retrospective study conducted at a single center, which may limit the generalizability of its findings to other populations or healthcare settings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Retrospective Study
Category Infection
Source Pubmed
PubMed ID 32807104
Year Published 2020
Journal BMC Infect Dis
MeSH Terms Anti-Bacterial Agents; C-Reactive Protein; Coinfection; Female; Humans; Hyperbaric Oxygenation; Infant; Influenza, Human; Length of Stay; Logistic Models; Male; Odds Ratio; Respiratory Syncytial Virus Infections; Retrospective Studies; Risk Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology