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Clinical Trial Zh Nevrol Psikhiatr Im S S Korsakova 2018

[Assessment of the efficacy of mexidol in the combination with hyperbaric oxygen in acute ischemic stroke]

Kulai N, Kovalchuk E — Zh Nevrol Psikhiatr Im S S Korsakova, 2018

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers compared the efficacy of mexidol combined with hyperbaric oxygenation (HBO) versus standard HBO alone in 112 patients with acute ischemic stroke.

What They Found

The study found that 48 patients receiving combination therapy (HBO + mexidol) experienced significantly more rapid normalization of acute phase indices compared to 64 patients receiving standard HBO alone. This rapid normalization was correlated with a reduction in neurological deficit.

What This Means for Canadian Patients

For Canadian patients experiencing acute ischemic stroke, this research suggests that combining mexidol with hyperbaric oxygenation could potentially accelerate recovery markers. This approach might lead to a quicker reduction in neurological deficits compared to standard hyperbaric oxygen therapy alone.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or with Canadian participants.

Study Limitations

The study's relatively small sample size of 112 patients may limit the generalizability of its findings.

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Study Details

Study Type Clinical Trial
Category Neurological
Source Pubmed
PubMed ID 29798984
Year Published 2018
Journal Zh Nevrol Psikhiatr Im S S Korsakova
MeSH Terms Brain Ischemia; Humans; Hyperbaric Oxygenation; Oxygen; Picolines; Platelet Aggregation Inhibitors; Stroke

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.