Clinical Trial Zh Nevrol Psikhiatr Im S S Korsakova 2018

Assessment of the efficacy of mexidol in the combination with hyperbaric oxygen in acute ischemic stroke

Kulai N, Kovalchuk E — Zh Nevrol Psikhiatr Im S S Korsakova, 2018

View Original on PubMed PMID 29798984

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers compared the efficacy of mexidol combined with hyperbaric oxygenation (HBO) versus standard HBO alone in 112 patients with acute ischaemic stroke.

What They Found

The study found that 48 patients receiving combination therapy (HBO + mexidol) experienced significantly more rapid normalization of acute phase indices compared to 64 patients receiving standard HBO alone. This rapid normalization was correlated with a reduction in neurological deficit.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or with Canadian participants.

Study Limitations

The study's relatively small sample size of 112 patients may limit the generalizability of its findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Trial
Category	Neurological
Source	Pubmed
PubMed ID	29798984
Year Published	2018
Journal	Zh Nevrol Psikhiatr Im S S Korsakova
MeSH Terms	Brain Ischemia; Humans; Hyperbaric Oxygenation; Oxygen; Picolines; Platelet Aggregation Inhibitors; Stroke

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology