Autoinflammatory skin disorders in inflammatory bowel diseases, pyoderma gangrenosum and Sweet's syndrome: a comprehensive review and disease classification criteria | Canada Hyperbarics Skip to main content
Review Clin Rev Allergy Immunol 2013

Autoinflammatory skin disorders in inflammatory bowel diseases, pyoderma gangrenosum and Sweet's syndrome: a comprehensive review and disease classification criteria

Marzano A, Ishak R, Saibeni S, Crosti C, Meroni P, Cugno M — Clin Rev Allergy Immunol, 2013

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a comprehensive review of pyoderma gangrenosum and Sweet's syndrome, two skin conditions often linked to inflammatory bowel diseases.

What They Found

They found that pyoderma gangrenosum (PG) and Sweet's syndrome (SS) are autoinflammatory skin conditions characterized by neutrophil accumulation. PG develops in 1-3% of inflammatory bowel disease patients, while SS is less common. Treatments for PG include wound care, topical and systemic medications, with hyperbaric oxygen noted as a supportive therapy.

What This Means for Canadian Patients

For Canadian patients with pyoderma gangrenosum, this review highlights various treatment options, including the potential for hyperbaric oxygen therapy as a supportive measure. While not a primary treatment, HBOT could be considered to aid healing in complex cases of these painful skin ulcers. Patients should discuss all treatment avenues with their healthcare providers.

Canadian Relevance

No direct Canadian connection identified. The study is not Canadian, and pyoderma gangrenosum and Sweet's syndrome are not Health Canada-recognised indications for HBOT.

Study Limitations

As a review article, this study synthesizes existing knowledge and does not present new clinical trial data or patient outcomes.

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Study Details

Study Type Review
Category Wound Care
Source Pubmed
PubMed ID 23334898
Year Published 2013
Journal Clin Rev Allergy Immunol
MeSH Terms Adrenal Cortex Hormones; Animals; Cell Movement; Complementary Therapies; Humans; Inflammatory Bowel Diseases; Neutrophils; Pyoderma Gangrenosum; Skin; Sweet Syndrome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.