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Case Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2014

Case report: hyperbaric oxygen and MRI findings in radiation-induced optic neuropathy.

Li CQ, Gerson S, Snyder B — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2014

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case report of a 78-year-old female with radiation-induced optic neuropathy (RON) who received two courses of hyperbaric oxygen (HBO2) therapy without corticosteroids.

What They Found

The patient's visual acuity subjectively and functionally improved during her first course of 30 HBO2 treatments and again during a second course of 40 treatments, but symptoms subsequently deteriorated after each course. Post-treatment MRI showed resolution of previously visible optic nerve contrast enhancement, marking this as the 27th reported case of RON treated with HBO2 and the first with radiologic and transient symptomatic improvement without concomitant steroid use.

What This Means for Canadian Patients

This case suggests that hyperbaric oxygen therapy might offer transient symptomatic and radiologic improvement for radiation-induced optic neuropathy. However, patients should be aware that any benefits observed may not be sustained, and more robust studies are needed to confirm efficacy.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a single case report, the findings are anecdotal and cannot be generalized to a broader patient population or establish definitive treatment efficacy.

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Study Details

Study Type Case Study
Category Radiation Injury
Source Pubmed
PubMed ID 24649718
Year Published 2014
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms Aged; Female; Humans; Hyperbaric Oxygenation; Magnetic Resonance Imaging; Optic Nerve; Optic Nerve Diseases; Radiation Injuries; Recurrence; Time Factors; Visual Acuity

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.