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Clinical Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 1997

Chronic radiation proctitis treated with hyperbaric oxygen.

Warren DC, Feehan P, Slade JB, Cianci PE — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 1997

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers treated 14 patients with chronic radiation proctitis with hyperbaric oxygen therapy (HBO2) between 1992 and 1995.

What They Found

Eight out of 14 patients (57%) experienced complete resolution of symptoms, and one patient had substantial improvement, resulting in a total response rate of 64%. The remaining five patients (36%) were non-responders, with three relapsing after initial improvement and two showing no symptomatic change.

What This Means for Canadian Patients

For Canadian patients suffering from chronic radiation proctitis, hyperbaric oxygen therapy may offer a viable treatment option to alleviate symptoms. This therapy could potentially improve quality of life for those experiencing this debilitating complication of radiation treatment.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor did it involve Canadian researchers or patients.

Study Limitations

A key limitation of this study is its small sample size of 14 patients and the lack of a control group, which limits the generalizability of the findings.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 9308141
Year Published 1997
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms Aged; Aged, 80 and over; Female; Gastrointestinal Hemorrhage; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Proctitis; Radiation Injuries; Radiotherapy Dosage; Rectal Diseases; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.