Study Bone Marrow Transplant 2012

Clinical effectiveness of hyperbaric oxygen therapy for BK-virus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation

Savva-Bordalo J, Pinho Vaz C, Sousa M, Branca R, Campilho F, Resende R, et al. — Bone Marrow Transplant, 2012

View Original on PubMed PMID 22080970

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively evaluated the effectiveness of hyperbaric oxygen therapy in 16 patients with BK-virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation.

What They Found

All 16 patients had macroscopic hematuria and BKV infection, receiving a median of 13 hyperbaric oxygen treatments. Fifteen patients (94%) experienced complete resolution of hematuria, and median urinary DNA BKV titers declined significantly after therapy (P<0.05). Patients who started treatment earlier after diagnosis responded sooner (P<0.05).

Canadian Relevance

This study does not have a direct Canadian connection.

Study Limitations

The study's retrospective design and small sample size limit the generalizability of its findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Study
Category	Infection
Source	Pubmed
PubMed ID	22080970
Year Published	2012
Journal	Bone Marrow Transplant
MeSH Terms	Adolescent; Adult; BK Virus; Bone Marrow Transplantation; Cystitis; Female; Hematologic Diseases; Hemorrhage; Humans; Hyperbaric Oxygenation; Infant; Male; Middle Aged; Polyomavirus Infections; Retrospective Studies; Time Factors; Transplantation, Homologous

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology