Clinical efficacy of hyperbaric oxygen combined with different timings of right median-nerve electrical stimulation in patients with brain injury-induced disorders of consciousness | Canada Hyperbarics Skip to main content
RCT Brain Behav 2022

Clinical efficacy of hyperbaric oxygen combined with different timings of right median-nerve electrical stimulation in patients with brain injury-induced disorders of consciousness

Liu Y, Liu Z, Yang Z, Zhao L, Li H — Brain Behav, 2022

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized controlled trial with 120 brain injury patients to compare hyperbaric oxygen therapy alone versus combined with right median-nerve electrical stimulation at different timings.

What They Found

All three groups showed significant improvement in Glasgow Coma Scale (GCS) scores (p < .05) and other neurological measures compared to before treatment. Patients receiving right median-nerve electrical stimulation concurrently with hyperbaric oxygen (Test Group 2) demonstrated the highest GCS scores and clinical efficacy, followed by those receiving stimulation after hyperbaric oxygen (Test Group 1), both outperforming the control group (p < .05).

What This Means for Canadian Patients

Canadian patients with brain injury-induced disorders of consciousness might benefit more from a treatment approach that combines hyperbaric oxygen therapy with right median-nerve electrical stimulation. This could potentially lead to improved recovery of consciousness and better neurological outcomes for these patients.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study's findings may be limited by its specific patient population and the need for further validation in larger, diverse cohorts.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 35920129
Year Published 2022
Journal Brain Behav
MeSH Terms Brain Injuries; Consciousness; Consciousness Disorders; Electric Stimulation; Humans; Hyperbaric Oxygenation; Oxygen; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.