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Clinical Study Annals of emergency medicine 1992

Clostridial myonecrosis resulting from subcutaneous epinephrine suspension injection.

Hallagan LF, Scott JL, Horowitz BC, Feied CF — Annals of emergency medicine, 1992

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported a case study of a 32-year-old asthmatic man who developed a life-threatening Clostridium perfringens infection following a subcutaneous epinephrine suspension injection.

What They Found

A 32-year-old asthmatic man developed a life-threatening Clostridium perfringens infection after receiving a subcutaneous epinephrine suspension injection. He underwent extensive surgical debridement, including forequarter amputation, hyperbaric oxygen therapy, and antibiotics, ultimately achieving a fair functional recovery. The authors noted no previously reported cases of gas gangrene following subcutaneous injection in otherwise healthy individuals.

Canadian Relevance

This specific case study has no direct Canadian connection. However, the medical principles and potential complications discussed are universally relevant to healthcare practice.

Study Limitations

A significant limitation of this study is its nature as a single case report, which limits the generalizability of its findings to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Infection
Source Pubmed
PubMed ID 1554186
Year Published 1992
Journal Annals of emergency medicine
MeSH Terms Adult; Amputation, Surgical; Anti-Bacterial Agents; Clostridium perfringens; Debridement; Epinephrine; Gas Gangrene; Humans; Hyperbaric Oxygenation; Injections, Subcutaneous; Male

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology