Cognitive enhancement of healthy young adults with hyperbaric oxygen: A preliminary resting-state fMRI study. | Canada Hyperbarics Skip to main content
Clinical Study Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2015

Cognitive enhancement of healthy young adults with hyperbaric oxygen: A preliminary resting-state fMRI study.

Yu R, Wang B, Li S, Wang J, Zhou F, Chu S, et al. — Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2015

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers used resting-state fMRI in 20 healthy young adults to examine the effect of hyperbaric oxygen (HBO) on cognitive performance and spontaneous brain activity compared to a placebo.

What They Found

Compared to the placebo group, the hyperbaric oxygen group showed significantly increased scores in spatial working memory and memory quotient. They also observed significantly increased regional homogeneity (ReHo) values in the left hippocampus, right inferior frontal, and lingual gyri, with enhanced functional connectivity in these areas.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor did it involve Canadian participants or researchers.

Study Limitations

This was a preliminary study with a small sample size of 20 healthy young adults, limiting the generalizability of the findings.

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Study Details

Study Type Clinical Study
Category Neurological
Source Pubmed
PubMed ID 25703942
Year Published 2015
Journal Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
MeSH Terms Adolescent; Brain; Brain Mapping; Case-Control Studies; Cognition; Female; Frontal Lobe; Hippocampus; Humans; Hyperbaric Oxygenation; Magnetic Resonance Imaging; Male; Memory; Occipital Lobe; Rest

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology