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Clinical Study Aesthetic surgery journal 2014 Canadian

Complications of injectable fillers, part 2: vascular complications.

DeLorenzi C — Aesthetic surgery journal, 2014

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This article reviewed the symptoms, risk factors, and treatment strategies for vascular complications, particularly ischemic events, arising from accidental intra-arterial injection of hyaluronic acid fillers.

What They Found

Vascular complications from hyaluronic acid filler injections, though rare, can cause significant tissue injury, presenting as skin blanching and dusky discoloration followed by blister formation and tissue slough a few days later. Prompt treatment involves immediate hyaluronidase, topical nitropaste, oral acetylsalicylic acid, warm compresses, and massage, with secondary options including intra-arterial hyaluronidase or hyperbaric oxygen therapy. Emergency preparedness with a "filler crash cart" is crucial for early intervention to reduce morbidity.

What This Means for Canadian Patients

Canadian patients considering injectable fillers should be aware of the rare but serious risk of vascular complications and discuss these with their practitioner. Seeking treatment from experienced clinicians who are prepared for emergencies, including having a "filler crash cart," can significantly improve outcomes if complications occur.

Canadian Relevance

This study was authored by a Canadian physician, providing insights directly relevant to clinical practice and patient safety within Canada's aesthetic medicine landscape.

Study Limitations

A key limitation is that the true incidence of vascular complications from injectable fillers remains unknown due to underreporting by clinicians.

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Study Details

Study Type Clinical Study
Category Systematic Reviews
Source Pubmed
PubMed ID 24692598
Year Published 2014
Journal Aesthetic surgery journal
MeSH Terms Biocompatible Materials; Cosmetic Techniques; Humans; Hyaluronic Acid; Injections, Intra-Arterial; Injections, Subcutaneous; Risk Factors; Treatment Outcome; Vascular Diseases

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.