What Researchers Did
Researchers conducted an international, multidisciplinary, modified Delphi consensus study to develop a core outcome set for future trials evaluating interventions for necrotising soft tissue infections (NSTI).
What They Found
Ninety-eight participants from 14 countries registered, with response rates of 86%, 69%, and 57% for the three rounds, respectively. Consensus was reached on five core outcome areas: death, surgical procedures (debridements and amputations), functional outcome among survivors, measures of sepsis, and resource use.
What This Means for Canadian Patients
This core outcome set will help standardize future research on necrotising soft tissue infections, leading to more consistent and comparable evidence. Ultimately, this could improve the development and evaluation of treatments, potentially leading to better care and outcomes for Canadian patients with NSTI.
Canadian Relevance
This study does not have a direct Canadian connection.
Study Limitations
A potential limitation is the decreasing participant response rate across the three Delphi rounds, which could affect the representativeness of the final consensus.