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Review Journal of the National Cancer Institute. Monographs 2019

Costs of Oral Complications of Cancer Therapies: Estimates and a Blueprint for Future Study.

Elting LS, Chang YC — Journal of the National Cancer Institute. Monographs, 2019

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a literature review to estimate the economic costs associated with oral complications of cancer therapies, including mucositis, xerostomia, and osteonecrosis.

What They Found

They found that oral mucositis incurred incremental costs of $5,000-$30,000 for radiation patients and $3,700 per chemotherapy cycle, with mucositis-related hospitalizations exceeding $70,000 for stem cell transplant recipients. Managing osteoradionecrosis cost $4,000-$35,000, potentially reaching $74,000, with hyperbaric oxygen therapy adding $10,000-$50,000, while xerostomia management with sialogogues cost $40-$200 monthly.

What This Means for Canadian Patients

Canadian cancer patients experiencing oral complications like mucositis or xerostomia face substantial financial burdens due to treatment costs and potential hospitalizations. Recognizing these high costs can encourage Canadian healthcare systems to prioritize proactive prevention and effective management strategies to improve patient outcomes and reduce economic strain.

Canadian Relevance

This study did not include Canadian data or participants, therefore it has no direct Canadian connection.

Study Limitations

A limitation of this review is its reliance on existing literature, which may have varied methodologies and data sources, and the cost estimates are specific to US dollars.

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Study Details

Study Type Review
Category Radiation Injury
Source Pubmed
PubMed ID 31425598
Year Published 2019
Journal Journal of the National Cancer Institute. Monographs
MeSH Terms Combined Modality Therapy; Cost of Illness; Cost-Benefit Analysis; Disease Management; Humans; Models, Theoretical; Mouth Diseases; Neoplasms

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.