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Clinical Study Current problems in cancer 1983

Current concepts in radiotherapy and their impact on oncology.

Fletcher GH, Current problems in cancer, 1983

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

A radiotherapist's essay reviews debates in cancer radiation treatment, focusing mainly on breast cancer care after mastectomy.

What They Found

A radiotherapist's commentary on breast cancer treatment states that postoperative radiation after mastectomy achieves a high degree of local and regional disease control, though the author writes it remains disputed whether this improves survival, and the abstract gives no sample size, dose, or statistical figures. The author also states that survival benefits from elective chemotherapy are only marginally proved in small subsets of patients and do not demonstrably affect survival rates in the overall patient population, with very little information available on its effect on local-regional control. The author notes that gross (visible) recurrence is harder to eradicate than subclinical disease treated with elective irradiation, and cites reports of poor local-regional control of breast cancer recurrences, including recurrences invading the brachial plexus described as intractable to treatment and chest wall recurrences described as a severe management problem.

What This Means for Canadian Patients

This abstract does not address hyperbaric oxygen therapy. It is an argument piece about radiation therapy and surgery in breast cancer, contending that local-regional treatment such as postoperative radiation after mastectomy has clear value for controlling disease in the treated area even though it is not proven to extend survival. The author also argues that combined radiation-and-surgery approaches are, in the author's own view, applied to only a small portion of eligible cancer patients.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This is an opinion-based commentary rather than a controlled study, presenting no original data, sample sizes, or statistical analysis to support its claims.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 6357638
Year Published 1983
Journal Current problems in cancer
MeSH Terms Breast Neoplasms; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Hyperthermia, Induced; Neoplasm Recurrence, Local; Neoplasms; Oxygen; Pelvic Neoplasms; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy Dosage

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology