Decompression-induced ocular tear film bubbles reflect the process of denitrogenation | Canada Hyperbarics Skip to main content
Study Invest Ophthalmol Vis Sci 2007

Decompression-induced ocular tear film bubbles reflect the process of denitrogenation

Mekjavic P, Mekjavic I — Invest Ophthalmol Vis Sci, 2007

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a two-part study to determine if bubbles observed in the eyes after hyperbaric exposure are caused by nitrogen leaving the body and to track how long this process takes.

What They Found

They found that the number of tear film bubbles significantly increased after subjects breathed air during dives to 2.0 ATA for 60 minutes, but not when they breathed pure oxygen. Similarly, reflectivity in the back of the eye increased after air dives but not oxygen dives, confirming nitrogen as the cause. Tear film bubbles remained elevated for at least two days after certain simulated dives.

What This Means for Canadian Patients

This research helps us understand how the body releases nitrogen after hyperbaric exposure, which is important for preventing or treating decompression sickness. For Canadian patients, especially divers, these findings suggest that eye examinations could potentially offer a non-invasive way to monitor nitrogen levels in the body after a dive. Understanding these processes can contribute to safer diving practices and more effective management of decompression-related issues.

Canadian Relevance

While the study authors and location are not identified as Canadian, the research covers decompression sickness, which is a Health Canada-recognised indication for hyperbaric oxygen therapy.

Study Limitations

The study involved a small number of participants (n=8 for each part), and the full results for the second part of the study were not provided in the abstract.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Study
Category Decompression Sickness
Source Pubmed
PubMed ID 17652748
Year Published 2007
Journal Invest Ophthalmol Vis Sci
MeSH Terms Air; Contact Lenses; Decompression; Decompression Sickness; Female; Humans; Hyperbaric Oxygenation; Lens, Crystalline; Male; Nitrogen; Tears; Time Factors; Ultrasonography; Vitreous Body

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This study relates to Decompression Sickness. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology