Delayed radiation injury to the retrobulbar optic nerves and chiasm. Clinical syndrome and treatment with hyperbaric oxygen and corticosteroids. | Canada Hyperbarics Skip to main content
Clinical Study Ophthalmology 1990

Delayed radiation injury to the retrobulbar optic nerves and chiasm. Clinical syndrome and treatment with hyperbaric oxygen and corticosteroids.

Roden D, Bosley TM, Fowble B, Clark J, Savino PJ, Sergott RC, et al. — Ophthalmology, 1990

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers treated 13 patients experiencing delayed vision loss after radiation therapy to the chiasm region with hyperbaric oxygen and corticosteroids.

What They Found

The study found that none of the 13 patients experienced vision improvement during treatment or during follow-up periods ranging from 1 to 4 years. These patients had developed painless, abrupt vision loss in one (6 patients) or both (7 patients) eyes between 4 and 35 months after receiving radiation doses of at least 4500 cGy.

What This Means for Canadian Patients

Canadian patients with delayed radiation-induced vision loss should understand that this specific treatment combination did not show efficacy in this study. Alternative management strategies or supportive care should be considered for this challenging condition.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A key limitation of this study is its small sample size of 13 patients and the absence of a comparative control group.

Was this summary helpful?

Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 2336273
Year Published 1990
Journal Ophthalmology
MeSH Terms Adrenal Cortex Hormones; Aged; Female; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Optic Chiasm; Optic Nerve; Radiation Injuries; Radiotherapy; Syndrome; Visual Acuity

Cite This Study

Share

Find a Canadian Clinic Treating Radiation Injury

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.