Disseminated intravascular coagulation, meningococcal infection, and ischemic changes affecting the lower extremities: a case study | Canada Hyperbarics Skip to main content
Case Report J Foot Ankle Surg 2010

Disseminated intravascular coagulation, meningococcal infection, and ischemic changes affecting the lower extremities: a case study

Herzog J, Morgan K, Paden M, Stone P — J Foot Ankle Surg, 2010

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described the case of a middle-aged woman who developed severe complications from a meningococcal infection.

What They Found

Researchers found that a middle-aged woman with Neisseria meningitidis infection developed a severe rash, leading to necrosis and wounds on her arms and legs. She also experienced heart problems, blood disorders, a C. difficile infection, depression, and temporary blindness. The study suggested that a low CH50 level in her immune system might have caused the meningococcemia, which then led to the limb damage.

What This Means for Canadian Patients

This case study highlights the severe and widespread tissue damage, including limb necrosis, that can result from meningococcal infections. For Canadian patients, this underscores the critical need for prompt diagnosis and aggressive treatment of such infections to prevent devastating complications like limb loss.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a case study, this report describes the experience of only one patient, meaning its findings cannot be broadly applied to all individuals with similar conditions.

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Study Details

Study Type Case Report
Category Wound Care
Source Pubmed
PubMed ID 20619693
Year Published 2010
Journal J Foot Ankle Surg
MeSH Terms Amputation, Surgical; Anti-Bacterial Agents; Blindness; Clostridioides difficile; Complement System Proteins; Depression; Dermatologic Surgical Procedures; Disseminated Intravascular Coagulation; Enterocolitis, Pseudomembranous; Extremities; Female; Humans; Hyperbaric Oxygenation; Ischemia; Meningococcal Infections; Middle Aged; Necrosis; Negative-Pressure Wound Therapy; Neisseria meningitidis; Purpura Fulminans; Skin; Skin Transplantation

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.