Clinical Guideline Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2019

Early treatment of frostbite with hyperbaric oxygen and pentoxifylline: a case report.

Robins M — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2019

View Original on PubMed PMID 31509908

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported a case of a 17-year-old male with frostbite treated early with hyperbaric oxygen and pentoxifylline.

What They Found

The patient received 13 hyperbaric oxygen treatments and oral pentoxifylline, initiated approximately two hours after rewarming. After 12 months of follow-up, both feet recovered full sensation, and the patient experienced no tissue loss or functional impairment.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a single case report, this study's findings cannot be generalized and lack a control group for comparison.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Guideline
Category	Neurological
Source	Pubmed
PubMed ID	31509908
Year Published	2019
Journal	Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms	Administration, Oral; Adolescent; Combined Modality Therapy; Foot; Frostbite; Humans; Hyperbaric Oxygenation; Male; Pentoxifylline; Rewarming; Time-to-Treatment; Toes; Vasodilator Agents

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology