Case Report Int Urol Nephrol 1996

Effective hyperbaric oxygenation with prostaglandin E1 for radiation cystitis and colitis after pelvic radiotherapy

Miura M, Sasagawa I, Kubota Y, Iijima Y, Sawamura T, Nakada T — Int Urol Nephrol, 1996

View Original on PubMed PMID 9061423

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers treated an 84-year-old woman with severe bleeding from her bladder and large intestine, which developed after radiation therapy for uterine cancer, using hyperbaric oxygen therapy and prostaglandin E1.

What They Found

The patient received hyperbaric oxygen therapy at 2 ATA for 60 minutes daily over 30 days, combined with prostaglandin E1 infusion. This combined treatment completely stopped her gross haematuria (blood in urine) and tarry stool (blood in feces). Endoscopic examinations also showed a reversal of the damage caused by radiation to her bladder (cystitis) and colon (colitis).

Canadian Relevance

This study is not Canadian, but it covers delayed radiation injury (radiation cystitis and colitis), which is a Health Canada-recognised indication for hyperbaric oxygen therapy.

Study Limitations

A significant limitation of this study is that it is a case report, detailing the experience of only one patient, which means the findings may not apply to everyone.

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Study Details

Study Type	Case Report
Category	Radiation Injury
Source	Pubmed
PubMed ID	9061423
Year Published	1996
Journal	Int Urol Nephrol
MeSH Terms	Aged; Aged, 80 and over; Alprostadil; Colitis; Combined Modality Therapy; Cystitis; Cystoscopy; Female; Humans; Hyperbaric Oxygenation; Pelvis; Radiation Injuries; Uterine Neoplasms

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology