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Meta-Analysis Journal of Indian Prosthodontic Society 2017

Effectiveness of hyperbaric oxygen therapy in irradiated maxillofacial dental implant patients: A systematic review with meta-analysis.

Shah DN, Chauhan CJ, Solanki JS, Journal of Indian Prosthodontic Society, 2017

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed and combined data from past studies to see whether hyperbaric oxygen therapy helps dental implants survive in patients whose jaw area was previously treated with radiation.

What They Found

This systematic review and meta-analysis of 14 studies found a lower implant failure rate in patients who received hyperbaric oxygen therapy compared to those who did not. The implant failure rate was 9.21% in the hyperbaric oxygen group, versus 22.44% in the non-hyperbaric oxygen group. The search covered databases including PubMed, Google Scholar, and the Cochrane Oral Health Group Trials Register, and started with 62 titles narrowed down to 14 included articles. Results were pooled using a random-effects meta-analysis model.

What This Means for Canadian Patients

For Canadian patients who have had radiation therapy to the jaw area and need dental implants, this review suggests hyperbaric oxygen therapy is linked to fewer implant failures compared to not using it. This applies specifically to irradiated maxillofacial patients undergoing prosthodontic rehabilitation, not to dental implants in general.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The meta-analysis pooled different study types, including randomized controlled trials, prospective and retrospective studies, and preliminary reports, which vary in design quality and can affect how reliable the combined result is.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Meta-Analysis
Category Radiation Injury
Source Pubmed
PubMed ID 28584411
Year Published 2017
Journal Journal of Indian Prosthodontic Society

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology