Effectiveness of hyperbaric oxygen therapy in SARS-CoV-2 pneumonia: the primary results of a randomised clinical trial | Canada Hyperbarics
RCT J Clin Med 2023

Effectiveness of hyperbaric oxygen therapy in SARS-CoV-2 pneumonia: the primary results of a randomised clinical trial

Siewiera J, Brodaczewska K, Jermakow N, et al. — J Clin Med, 2023

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized clinical trial with 28 moderate-to-severe COVID-19 patients to assess the safety and efficacy of hyperbaric oxygen therapy (HBOT) as an adjunct treatment.

What They Found

The study found no deaths in the hyperbaric oxygen therapy (HBOT) group compared to 3 deaths in the control group, with no adverse events reported for HBOT. Patients receiving HBOT required lower oxygen delivery and showed decreases in inflammatory markers like CRP, ferritin, and LDH, alongside an increase in CD3 T cells.

What This Means for Canadian Patients

For Canadian patients with moderate-to-severe COVID-19, hyperbaric oxygen therapy (HBOT) could potentially offer a safe adjunctive treatment to reduce inflammation and improve oxygenation. This therapy might help decrease the need for advanced respiratory support and potentially lower mortality rates, though further research is needed.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or with Canadian participants.

Study Limitations

A primary limitation of this study is its small sample size of only 28 patients, which limits the generalizability of the findings.

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Study Details

Study Type RCT
Category COVID-19 / Long COVID
Source Pubmed
PubMed ID 36614808
Year Published 2023
Journal J Clin Med

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.