Effects and mechanism of stem cells from human exfoliated deciduous teeth combined with hyperbaric oxygen therapy in type 2 diabetic rats. | Canada Hyperbarics Skip to main content
Clinical Study Clinics (Sao Paulo, Brazil) 2020

Effects and mechanism of stem cells from human exfoliated deciduous teeth combined with hyperbaric oxygen therapy in type 2 diabetic rats.

Xu Y, Chen J, Zhou H, Wang J, Song J, Xie J, et al. — Clinics (Sao Paulo, Brazil), 2020

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effects of stem cells from human exfoliated deciduous teeth (SHED) combined with hyperbaric oxygen (HBO) therapy on type 2 diabetic rats.

What They Found

The combination therapy or SHED therapy alone significantly decreased blood glucose, insulin resistance, serum lipids, and pro-inflammatory cytokines, while increasing body weight and serum insulin in diabetic rats. These treatments also improved the morphology and structure of pancreatic islets, leading to an increase in insulin-positive cells.

Canadian Relevance

This study has no direct Canadian connection as it was conducted outside of Canada and did not involve Canadian researchers or participants.

Study Limitations

A primary limitation of this study is that its findings are based on an animal model, which may not directly translate to human physiology and clinical outcomes.

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Study Details

Study Type Clinical Study
Category Uncategorised
Source Pubmed
PubMed ID 32520222
Year Published 2020
Journal Clinics (Sao Paulo, Brazil)
MeSH Terms Animals; China; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Hyperbaric Oxygenation; Insulin; Insulin-Secreting Cells; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Rats; Rats, Sprague-Dawley; Stem Cells

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.