Effects of adjuvant hyperbaric oxygen therapy and real-time fluorescent imaging on deep sternal wound infection: a retrospective study | Canada Hyperbarics Skip to main content
Retrospective Study J Wound Care 2025

Effects of adjuvant hyperbaric oxygen therapy and real-time fluorescent imaging on deep sternal wound infection: a retrospective study

Li T, Lin C, Peng C, Wu Y, Hsieh T, Lee C, et al. — J Wound Care, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively compared outcomes in 55 patients with deep sternal wound infection after cardiac surgery: 22 received HBOT plus standard care, and 33 received standard care plus real-time fluorescent imaging (RTFI) for guided debridement.

What They Found

HBOT reduced in-hospital mortality compared to the non-HBOT baseline. The RTFI group showed superior infection control metrics including lower reinfection rates and shorter healing time. HBOT was specifically credited with mortality benefit.

What This Means for Canadian Patients

Deep sternal wound infection after open heart surgery is a life-threatening complication. HBOT appears to reduce mortality in this context. Canadian cardiac surgery centers should consider integrating HBOT access into their wound complication protocols for post-sternotomy infections.

Canadian Relevance

No direct Canadian connection identified, though the MolecuLight imaging device used in this study is a Canadian product (MolecuLight Inc., Toronto).

Study Limitations

The retrospective design with different patient groups receiving different additional interventions makes it difficult to isolate HBOT independent contribution to mortality reduction.

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Study Details

Study Type Retrospective Study
Category Wound Care
Source Pubmed
PubMed ID 39797755
Year Published 2025
Journal J Wound Care
MeSH Terms Humans; Hyperbaric Oxygenation; Retrospective Studies; Male; Female; Middle Aged; Surgical Wound Infection; Aged; Debridement; Negative-Pressure Wound Therapy; Optical Imaging; Sternotomy; Osteomyelitis; Treatment Outcome; Anti-Bacterial Agents; Adult

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.