RCT Zhonghua nan ke xue = National journal of andrology 2009

Effects of hyperbaric oxygen on tumor growth in the mouse model of LNCaP prostate cancer cell line.

Tang H, Zhang ZY, Ge JP, Zhou WQ, Gao JP — Zhonghua nan ke xue = National journal of andrology, 2009

View Original on PubMed PMID 19852272

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers randomised 30 mice with LNCaP prostate cancer cells to receive either 20 sessions of hyperbaric oxygen or normobaric air to assess its effect on tumour growth.

What They Found

After 28 days, tumour volume was 120 +/- 7.9 mm3 in the hyperbaric oxygen group and 122 +/- 8.2 mm3 in the control group. No significant differences were observed between the groups for tumour volume, microvessel density, or markers of apoptosis and proliferation (P > 0.05), indicating hyperbaric oxygen did not promote tumour growth.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A primary limitation is that this study was conducted in a mouse model, limiting direct generalizability to human patients.

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Study Details

Study Type	RCT
Category	Radiation Injury
Source	Pubmed
PubMed ID	19852272
Year Published	2009
Journal	Zhonghua nan ke xue = National journal of andrology
MeSH Terms	Animals; Cell Line, Tumor; Humans; Hyperbaric Oxygenation; Male; Mice; Mice, SCID; Prostatic Neoplasms; Xenograft Model Antitumor Assays

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology