Effects of hyperbaric oxygen therapy on spinal cord injury: a systematic review and meta-analysis of randomized controlled trials | Canada Hyperbarics Skip to main content
Meta-Analysis PLoS ONE 2021

Effects of hyperbaric oxygen therapy on spinal cord injury: a systematic review and meta-analysis of randomized controlled trials

Huang H, Xue L, Zhang X, et al. — PLoS ONE, 2021

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review and meta-analysis of 11 randomized controlled trials involving 875 participants to evaluate the effects of hyperbaric oxygen therapy on motor function, sensory function, and psychology in patients with spinal cord injury.

What They Found

The meta-analysis of 11 studies with 875 participants found that hyperbaric oxygen therapy significantly improved the ASIA motor score (mean difference 15.84, 95% CI 9.04 to 22.64). It also statistically promoted the ASIA sensory score (mean difference 66.30, 95% CI 53.44 to 79.16).

What This Means for Canadian Patients

For Canadian patients with spinal cord injury, these findings suggest that hyperbaric oxygen therapy could potentially lead to improvements in motor and sensory function. This may contribute to enhanced recovery and a better quality of life following their injury.

Canadian Relevance

This study does not have a direct Canadian connection.

Study Limitations

A significant limitation of this meta-analysis was the high heterogeneity observed across the included studies for both motor (I2=87%) and sensory (I2=95%) outcomes.

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Study Details

Study Type Meta-Analysis
Category Neurological
Source Pubmed
PubMed ID 33935063
Year Published 2021
Journal PLoS ONE

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.