Efficacy and safety of hyperbaric oxygen therapy for Parkinson's disease with cognitive dysfunction: protocol for a systematic review and meta-analysis | Canada Hyperbarics Skip to main content
Meta-Analysis BMJ Open 2024

Efficacy and safety of hyperbaric oxygen therapy for Parkinson's disease with cognitive dysfunction: protocol for a systematic review and meta-analysis

Tan W, Pan Z, Xie F — BMJ Open, 2024

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers planned a systematic review and meta-analysis to gather and analyze all available randomized controlled trials testing whether hyperbaric oxygen therapy (HBOT) can improve thinking and memory problems in people with Parkinson's disease.

What They Found

This is a protocol paper, no results are available yet. The review will search databases including PubMed and Cochrane Library for trials published up to April 2024. Results will be analyzed using RevMan 5.3 and Stata 15.0, with bias assessed by the Cochrane risk-of-bias tool.

What This Means for Canadian Patients

Parkinson's disease affects roughly 100,000 Canadians, and cognitive decline is one of its most disabling features. This review, once completed, will provide the clearest evidence yet on whether HBOT should be considered for Parkinson's-related cognitive impairment. Canadians with Parkinson's and their neurologists should watch for this review's publication.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This is a study protocol only, no actual patient data has been collected or analyzed yet, so no clinical conclusions can be drawn.

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Study Details

Study Type Meta-Analysis
Category Neurological
Source Pubmed
PubMed ID 39572094
Year Published 2024
Journal BMJ Open
MeSH Terms Humans; Cognitive Dysfunction; Hyperbaric Oxygenation; Meta-Analysis as Topic; Parkinson Disease; Quality of Life; Research Design; Systematic Reviews as Topic

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.