FDG-PET may predict the effectiveness of hyperbaric oxygen therapy in a patient with bisphosphonate-related osteonecrosis of the jaw: report of a case. | Canada Hyperbarics Skip to main content
Clinical Study Odontology 2015

FDG-PET may predict the effectiveness of hyperbaric oxygen therapy in a patient with bisphosphonate-related osteonecrosis of the jaw: report of a case.

Fatema CN, Sato J, Yamazaki Y, Hata H, Hattori N, Shiga T, et al. — Odontology, 2015

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on an 80-year-old woman with bisphosphonate-related osteonecrosis of the jaw (BRONJ) who received hyperbaric oxygen therapy and other treatments, observing changes with FDG-PET.

What They Found

After 20 sessions of hyperbaric oxygen therapy, the patient's clinical symptoms resolved. Concurrently, the SUVmax of FDG-PET decreased significantly from 4.5 to 2.5, while other imaging modalities showed no notable changes. Following minor surgery and additional HBO therapy, the patient's recovery was excellent.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The primary limitation of this study is that it is a single case report, meaning its findings cannot be generalized to a broader patient population without further research.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Uncategorised
Source Pubmed
PubMed ID 23907202
Year Published 2015
Journal Odontology
MeSH Terms Aged, 80 and over; Bisphosphonate-Associated Osteonecrosis of the Jaw; Female; Fluorodeoxyglucose F18; Humans; Hyperbaric Oxygenation; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology