What Researchers Did
Researchers investigated atherosclerotic ischaemia of the foot skin using hyperbaric oxygen and the vasodilating effect of tolazoline hydrochloride.
What They Found
They found that ischaemic feet had significantly higher blood flow than normal, with two subgroups showing significantly different flows. This high blood flow appeared to be an attempt to meet tissue oxygen needs, but often without clear benefit to the ischaemic skin. They suggest that local, rather than regional, blood flow insufficiency causes skin lesions in peripheral vascular disease.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
The abstract does not detail the study's sample size or specific quantitative blood flow measurements, limiting the generalizability of its findings.