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Clinical Trial J Neurooncol 2007

Fractionated stereotactic radiotherapy using gamma unit after hyperbaric oxygenation on recurrent high-grade gliomas

Kohshi K, Yamamoto H, Nakahara A, Katoh T, Takagi M — J Neurooncol, 2007

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated combining hyperbaric oxygen therapy with fractionated stereotactic radiotherapy for 25 patients with recurrent high-grade gliomas.

What They Found

The median survival time after treatment was 19 months for patients with anaplastic astrocytoma and 11 months for those with glioblastoma multiforme. Seven patients (28%) underwent subsequent surgery, with 4 of these showing no viable cancer cells and surviving for 50-78 months.

What This Means for Canadian Patients

This approach could offer a potential new treatment option for Canadian patients facing recurrent high-grade gliomas, a condition with limited treatment options. The findings suggest that combining hyperbaric oxygen with radiotherapy might improve survival outcomes for this challenging cancer.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This was a small study involving only 25 patients, and further larger-scale research is needed to confirm these preliminary findings.

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Study Details

Study Type Clinical Trial
Category Radiation Injury
Source Pubmed
PubMed ID 17120158
Year Published 2007
Journal J Neurooncol
MeSH Terms Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Neoplasm Recurrence, Local; Radiosurgery; Survival Analysis; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.