Clinical Study Oxidative medicine and cellular longevity 2022

HBO Alleviates Neural Stem Cell Pyroptosis via lncRNA-H19/miR-423-5p/NLRP3 Axis and Improves Neurogenesis after Oxygen Glucose Deprivation.

Ye Y, Feng Z, Tian S, Yang Y, Jia Y, Wang G, et al. — Oxidative medicine and cellular longevity, 2022

View Original on PubMed PMID 35178162

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated how hyperbaric oxygen (HBO) treatment affects neural stem cell (NSC) pyroptosis, proliferation, and differentiation after oxygen-glucose deprivation (OGD), mimicking stroke conditions.

What They Found

The abstract outlines the study's objective to explore the impact of hyperbaric oxygen (HBO) on neural stem cell (NSC) pyroptosis, proliferation, and differentiation following oxygen-glucose deprivation (OGD). It does not provide specific numerical results or findings from the investigation.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation is that the provided abstract only describes the study's aims and does not present any experimental results or findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Study
Category	Neurological
Source	Pubmed
PubMed ID	35178162
Year Published	2022
Journal	Oxidative medicine and cellular longevity
MeSH Terms	Animals; Cell Differentiation; Glucose; Humans; MicroRNAs; Neural Stem Cells; Neurogenesis; Oxygen; Pyroptosis; RNA, Long Noncoding; Transfection

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology