HOTFy: randomised clinical trial for hyperbaric oxygen therapy in fibromyalgia | Canada Hyperbarics Skip to main content
RCT BMJ Open 2026

HOTFy: randomised clinical trial for hyperbaric oxygen therapy in fibromyalgia

da Mota Neto J, Mendes A, Magalhães Martins A, Teixeira De Landa A, de Oliveira Fraga R, de Souza V, et al. — BMJ Open, 2026

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized clinical trial in Brazil to see if hyperbaric oxygen therapy, given at 2.3 atmospheres absolute for 90 minutes, five times a week over 8 weeks, improved symptoms for women with fibromyalgia.

What They Found

The abstract for this study details the design and methods used to evaluate hyperbaric oxygen therapy for fibromyalgia. It describes a randomized, cross-over trial involving 56 women, but it does not present any specific findings, numbers, or outcomes from the research.

Canadian Relevance

This study was conducted in Brazil and does not include Canadian authors or participants. Fibromyalgia is not a Health Canada-recognized indication for hyperbaric oxygen therapy. No direct Canadian connection identified.

Study Limitations

A limitation of this study is that it was conducted at a single centre, which may affect how broadly the findings can be applied to other populations.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 42225366
Year Published 2026
Journal BMJ Open
MeSH Terms Humans; Fibromyalgia; Hyperbaric Oxygenation; Female; Middle Aged; Adult; Cross-Over Studies; Brazil; Treatment Outcome; Aged; Pain Measurement; Single-Blind Method; Quality of Life; Young Adult; Adolescent; Diving and Hyperbaric Medicine

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: June 5, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology