Hyperbaric oxygen corrects sacral plexopathy due to osteoradionecrosis appearing 15 years after pelvic irradiation. | Canada Hyperbarics Skip to main content
Clinical Study Clinical oncology (Royal College of Radiologists (Great Britain)) 1999 Canadian

Hyperbaric oxygen corrects sacral plexopathy due to osteoradionecrosis appearing 15 years after pelvic irradiation.

Videtic GM, Venkatesan VM — Clinical oncology (Royal College of Radiologists (Great Britain)), 1999

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers describe a case where hyperbaric oxygen therapy successfully treated sacral plexopathy caused by osteoradionecrosis, appearing 15 years after pelvic irradiation for bladder cancer.

What They Found

A 55-year-old woman developed sacral plexopathy 15 years after receiving pelvic irradiation for bladder leiomyosarcoma. Investigations revealed osteoradionecrosis of the sacrum. Following hyperbaric oxygen therapy, her neurological symptoms progressively resolved.

Canadian Relevance

This case study is relevant to Canadian patients as it highlights a potential treatment for a severe, late complication of radiation therapy that could affect individuals across Canada.

Study Limitations

The primary limitation of this study is that it describes a single case, which limits the generalizability of its findings to a broader patient population.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 10465478
Year Published 1999
Journal Clinical oncology (Royal College of Radiologists (Great Britain))
MeSH Terms Bone Diseases; Female; Humans; Hyperbaric Oxygenation; Leiomyosarcoma; Lumbosacral Plexus; Middle Aged; Osteoradionecrosis; Peripheral Nervous System Diseases; Radiotherapy; Urinary Bladder Neoplasms

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology