What Researchers Did
Researchers observed 4 cases of chronically recurrent mandibular osteomyelitis in children and adolescents over 5 years, with 3 receiving adjuvant hyperbaric oxygen therapy (HBO) alongside high-dose antibiotics.
What They Found
All 3 patients who received adjuvant HBO remained symptom-free for 20 to 74 months, with a mean follow-up of 41 months. These 3 patients were considered healed, suggesting a positive outcome associated with HBO.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
The primary limitation is the very small number of cases (n=4, with 3 receiving HBO), which prevents definitive conclusions about HBO's efficacy.