Meta-Analysis PloS one 2022

Hyperbaric oxygen in children with cerebral palsy: A systematic review of effectiveness and safety.

Laureau J, Pons C, Letellier G, Gross R — PloS one, 2022

View Original on PubMed PMID 36240157

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a systematic review and meta-analysis to evaluate the effectiveness and safety of hyperbaric oxygen therapy (HBOT) for children with cerebral palsy (CP).

What They Found

The review of five randomised controlled trials (RCTs) found high-level evidence that HBOT is ineffective in improving motor and cognitive functions in children with CP. Furthermore, moderate-level evidence indicated HBOT is associated with a higher rate of adverse events, with middle ear barotrauma affecting up to 50% of children.

Canadian Relevance

This study does not have a specific Canadian connection.

Study Limitations

A limitation of this review is the inclusion of several low-quality observational studies alongside the higher-quality randomised controlled trials.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Meta-Analysis
Category	Neurological
Source	Pubmed
PubMed ID	36240157
Year Published	2022
Journal	PloS one
MeSH Terms	Cerebral Palsy; Child; Humans; Hyperbaric Oxygenation

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology