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Clinical Study Cancer 1977

Hyperbaric oxygen in radiation therapy.

Glassburn JR, Brady LW, Plenk HP — Cancer, 1977

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

The researchers reviewed the existing evidence regarding the use of hyperbaric oxygen in conjunction with radiation therapy for cancer treatment.

What They Found

The researchers found that despite some impressive results in studies, particularly for head and neck tumours, it was not unequivocally demonstrated that hyperbaric oxygen radiation therapy was superior to conventional methods. They noted that any survival gain from hyperbaric oxygen would likely be limited, especially in advanced disease stages, though even a 5% to 10% improvement in survival could save many lives.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A key limitation highlighted by the researchers was the lack of unequivocally demonstrated superiority of hyperbaric oxygen over conventional radiotherapy, necessitating further well-controlled studies.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 319896
Year Published 1977
Journal Cancer
MeSH Terms Animals; Clinical Trials as Topic; Ear Diseases; Female; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Intestinal Diseases; Lung Neoplasms; Myelitis; Neoplasm Metastasis; Neoplasms; Radiotherapy Dosage; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology