Hyperbaric oxygen in the treatment of perineal Crohn's disease era of infliximab: a renewal interest?. | Canada Hyperbarics Skip to main content
RCT La Tunisie medicale 2012

Hyperbaric oxygen in the treatment of perineal Crohn's disease era of infliximab: a renewal interest?.

Bedioui H, Makni A, Magherbi H, Ben Safta Z — La Tunisie medicale, 2012

View Original on PubMed PMID 22693080
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a literature review to assess the efficacy of hyperbaric oxygen therapy (HBO) in treating refractory anal fistulas in Crohn's disease.

What They Found

Among 22 patients from four selected publications, 15 (68.18%) achieved remission with hyperbaric oxygen therapy, a rate comparable to infliximab's 66%. Adverse events were observed in 2 patients (16.6%).

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The findings are limited by this being a literature review based on a small number of studies (four publications) and a total of only 22 patients.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Uncategorised
Source Pubmed
PubMed ID 22693080
Year Published 2012
Journal La Tunisie medicale
MeSH Terms Adult; Antibodies, Monoclonal; Crohn Disease; Female; Gastrointestinal Agents; Humans; Hyperbaric Oxygenation; Infliximab; Intestinal Fistula; Male; Middle Aged; Perineum; Treatment Failure; Treatment Outcome; Young Adult

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology