What Researchers Did
Researchers reviewed hyperbaric oxygen therapy and other adjunctive treatments for zygomycosis, a life-threatening invasive fungal infection.
What They Found
Current treatment for zygomycosis involves amphotericin B lipid formulations combined with surgery, sometimes with caspofungin, and posaconazole for consolidation. While adjunctive therapies like hyperbaric oxygen therapy, immunomodulatory cytokines, and iron starvation are explored, there is no clinical evidence supporting their general effectiveness in patients with zygomycosis.
What This Means for Canadian Patients
Canadian patients with zygomycosis should continue to receive standard care, including antifungal medications and surgery. Adjunctive treatments like hyperbaric oxygen therapy currently lack sufficient clinical evidence to be routinely recommended.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
The study highlights a lack of robust clinical evidence for the general effectiveness of adjunctive treatments for zygomycosis, necessitating further investigation.