Review Undersea Hyperb Med 2011

Hyperbaric oxygen therapy and promoting neurological recovery following nerve trauma

Nazario J, Kuffler D — Undersea Hyperb Med, 2011

View Original on PubMed PMID 22013761

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This review examined the mechanisms by which hyperbaric oxygen therapy (HBO2T) could promote neurological recovery following nerve trauma.

What They Found

HBO2T induces physiological actions that meet many requirements for wound healing and axon regeneration. The review found numerous animal and clinical examples suggesting benefits of HBO2T in promoting neurological recovery after nerve trauma, concluding that HBO2T triggers most mechanisms needed for axon regeneration.

Canadian Relevance

This review does not have a direct Canadian connection.

Study Limitations

The review primarily discusses mechanisms and anecdotal evidence, noting that nerve traumas are not yet an indicated use for hyperbaric oxygen therapy.

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Study Details

Study Type	Review
Category	Wound Care
Source	Pubmed
PubMed ID	22013761
Year Published	2011
Journal	Undersea Hyperb Med
MeSH Terms	Animals; Axons; Bacterial Infections; Central Nervous System Diseases; Humans; Hyperbaric Oxygenation; Intercellular Signaling Peptides and Proteins; Models, Animal; Neovascularization, Physiologic; Nerve Regeneration; Peripheral Nervous System Diseases; Rats; Wound Healing; Wounds and Injuries

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology