Hyperbaric oxygen therapy for chronic radiotherapy-related adverse effects: A clinically focused review. | Canada Hyperbarics
RCT CA: a cancer journal for clinicians 2026

Hyperbaric oxygen therapy for chronic radiotherapy-related adverse effects: A clinically focused review.

Dejonckheere CS, Käsmann L, Schmeel LC, Walter S, Anzböck T, Dreyer S, et al. — CA: a cancer journal for clinicians, 2026

Tier 2 — Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

The authors conducted a clinically focused review to critically evaluate evidence for hyperbaric oxygen therapy in managing chronic radiotherapy-related adverse effects.

What They Found

The review found hyperbaric oxygen therapy to be a potential adjunctive treatment for mitigating chronic radiation-induced conditions such as skin fibrosis, bone necrosis, radiation cystitis, and proctitis. Researchers critically evaluated evidence from randomized trials, cohort studies, and real-world data, identifying gaps in knowledge regarding patient selection and optimal treatment protocols.

What This Means for Canadian Patients

Canadian patients experiencing chronic adverse effects from radiotherapy, such as fibrosis or cystitis, may find hyperbaric oxygen therapy to be a beneficial adjunctive treatment. This therapy could potentially improve their quality of life by promoting tissue healing and remodeling in affected areas.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The review identified limitations in current knowledge, specifically regarding optimal patient selection, treatment protocols, and long-term outcomes for hyperbaric oxygen therapy.

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Study Details

Study Type RCT
Category Radiation Injury
Source Pubmed
PubMed ID 41385271
Year Published 2026
Journal CA: a cancer journal for clinicians
MeSH Terms Humans; Hyperbaric Oxygenation; Radiation Injuries; Neoplasms; Radiotherapy; Quality of Life; Chronic Disease; Cystitis; Randomized Controlled Trials as Topic; Osteoradionecrosis; Proctitis

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.