What Researchers Did
Researchers conducted a systematic review to evaluate the effect of hyperbaric oxygen therapy (HBOT) on local late radiation toxicity (LRT) symptoms in breast cancer patients.
What They Found
Nine studies, totaling 1308 patients, found that post-HBOT, significant reductions were observed in pain (4/5 studies), lymphedema (4/7 studies), and improved arm and shoulder mobility (2/2 studies). Additionally, fibrosis and skin problems were reduced in 1/2 studies each.
What This Means for Canadian Patients
Hyperbaric oxygen therapy may offer a potential treatment option for Canadian breast cancer patients experiencing late radiation toxicity symptoms like pain, lymphedema, or reduced mobility. Patients should discuss this therapy with their healthcare providers to determine if it is a suitable option for their specific condition.
Canadian Relevance
This systematic review did not include any studies specifically conducted in Canada or with Canadian patients.
Study Limitations
The evidence for HBOT's effectiveness is limited due to small sample sizes and a substantial risk of bias in most included studies.