Hyperbaric oxygen therapy for people with autism... (2016 study) Skip to main content
Systematic Review Cochrane 2016 Cochrane

Hyperbaric oxygen therapy for people with autism spectrum disorder (ASD)

Xiong T, Chen H, Luo R, et al., Cochrane, 2016

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers reviewed the evidence on whether hyperbaric oxygen therapy helps children and adults with autism spectrum disorder.

What They Found

This Cochrane systematic review found no evidence that hyperbaric oxygen therapy improves social interaction, communication, behavioral problems, or cognition in people with autism spectrum disorder, based on the one trial that met its inclusion criteria. That trial randomly assigned 60 children with an autism spectrum disorder diagnosis to hyperbaric oxygen therapy or a sham treatment. The reviewers rated the overall quality of the evidence as low, pointing to the small sample size and wide confidence intervals. The trial also reported adverse effects linked to treatment.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The review's conclusions rest on just one trial of 60 participants, with the reviewers themselves rating the evidence as low quality due to the small sample size, wide confidence intervals, and other unresolved methodological problems.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Systematic Review
Category Neurological
Source Pubmed
PubMed ID 27737490
Year Published 2016
Journal Cochrane

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology