What Researchers Did
Researchers conducted a retrospective analysis to evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) for treating hemorrhagic cystitis and proctitis caused by pelvic or prostate-only radiation therapy.
What They Found
Among 15 evaluated patients, the mean LENT-SOMA score for hemorrhagic cystitis reduced from 0.78 to 0.20, and for proctitis from 0.66 to 0.26. Complete resolution of hematuria was observed in 81% (9 out of 11) of patients, with recurrence occurring in 36% after a median of 10 months.
What This Means for Canadian Patients
This therapy could offer a treatment option for Canadian patients experiencing severe bleeding complications from pelvic radiation that are resistant to other treatments. It may help reduce symptoms and improve quality of life for those suffering from radiation-induced cystitis or proctitis.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
The study's retrospective design, small sample size of 19 patients, and loss to follow-up for some patients limit the generalizability of its findings.