Meta-Analysis Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2016

Hyperbaric oxygen therapy for the treatment of traumatic brain injury: a meta-analysis.

Wang F, Wang Y, Sun T, Yu HL — Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2016

View Original on PubMed PMID 26746238

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a meta-analysis of eight prospective studies to evaluate the outcomes of hyperbaric oxygen therapy (HBOT) in patients with mild to severe traumatic brain injury (TBI).

What They Found

The HBOT group showed a higher post-treatment Glasgow Coma Scale (GCS) score (pooled difference in means = 3.13, 95% CI 2.34-3.92, P < 0.001), greater improvement in Glasgow Outcome Score (GOS), and lower mortality compared to the control group. However, no significant change in the post-traumatic stress disorder (PTSD) score was observed.

Canadian Relevance

This meta-analysis did not include any Canadian studies or participants, so direct Canadian relevance is not established. Further research involving Canadian populations would be needed to confirm these findings locally.

Study Limitations

The abstract does not detail specific limitations regarding the quality or heterogeneity of the included studies in this meta-analysis.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Meta-Analysis
Category	Neurological
Source	Pubmed
PubMed ID	26746238
Year Published	2016
Journal	Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
MeSH Terms	Adult; Brain Injuries, Traumatic; Databases, Factual; Female; Glasgow Coma Scale; Humans; Hyperbaric Oxygenation; Male; Treatment Outcome; Young Adult

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology