Systematic Review Cochrane Database Syst Rev 2012 Cochrane

Hyperbaric oxygen therapy for vascular dementia

Xiao Y, Wang J, Jiang S, Luo H — Cochrane Database Syst Rev, 2012

View Original on PubMed PMID 22786527

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review to assess the efficacy and safety of hyperbaric oxygen therapy (HBOT) for vascular dementia (VaD), used alone or as an adjuvant treatment.

What They Found

Only one randomised controlled trial involving 64 patients was included in the review. This study compared HBOT as an adjuvant to donepezil with donepezil alone. Due to the limited number of included studies, the review could not draw definitive conclusions regarding the efficacy and safety of HBOT for VaD.

Canadian Relevance

This systematic review does not have a direct Canadian connection.

Study Limitations

The primary limitation of this systematic review is the inclusion of only one small study, which prevents drawing robust conclusions about hyperbaric oxygen therapy for vascular dementia.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Systematic Review
Category	Neurological
Source	Pubmed
PubMed ID	22786527
Year Published	2012
Journal	Cochrane Database Syst Rev
MeSH Terms	Cognition; Combined Modality Therapy; Dementia, Vascular; Donepezil; Humans; Hyperbaric Oxygenation; Indans; Nootropic Agents; Piperidines; Randomized Controlled Trials as Topic

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology