Hyperbaric oxygen therapy improves the effect of keloid surgery and radiotherapy by reducing the recurrence rate. | Canada Hyperbarics Skip to main content
Clinical Study Journal of Zhejiang University. Science. B 2018

Hyperbaric oxygen therapy improves the effect of keloid surgery and radiotherapy by reducing the recurrence rate.

Song KX, Liu S, Zhang MZ, Liang WZ, Liu H, Dong XH, et al. — Journal of Zhejiang University. Science. B, 2018

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers randomized 240 patients with keloids to receive either hyperbaric oxygen therapy (HBOT) in addition to surgery and radiotherapy, or surgery and radiotherapy alone.

What They Found

The recurrence rate was significantly lower in the HBOT group (5.97%) compared to the control group (14.15%, P<0.05). Patients receiving HBOT also reported greater satisfaction (P<0.05), and their recurrent scar tissue showed lower levels of inflammatory factors.

What This Means for Canadian Patients

For Canadian patients undergoing keloid treatment, adding hyperbaric oxygen therapy to surgery and radiotherapy may significantly reduce the chance of recurrence. This could lead to better long-term outcomes and increased patient satisfaction with their scar management.

Canadian Relevance

This study was not conducted in Canada and does not have a direct Canadian connection.

Study Limitations

The study's generalizability may be limited, and further research is needed to confirm long-term efficacy and optimal HBOT protocols.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 30387335
Year Published 2018
Journal Journal of Zhejiang University. Science. B
MeSH Terms Adolescent; Adult; Female; Humans; Hyperbaric Oxygenation; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-6; Keloid; Male; Middle Aged; NF-kappa B p50 Subunit; Perfusion; Recurrence; Surveys and Questionnaires

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.