Hyperbaric oxygen therapy in children with post-concussion syndrome improves cognitive and behavioral function: a randomized controlled trial | Canada Hyperbarics Skip to main content
RCT Sci Rep 2022

Hyperbaric oxygen therapy in children with post-concussion syndrome improves cognitive and behavioral function: a randomized controlled trial

Hadanny A, Catalogna M, Yaniv S, Stolar O, Rothstein L, Shabi A, et al. — Sci Rep, 2022

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized, sham-controlled, double-blind trial to evaluate hyperbaric oxygen therapy (HBOT) in 25 children aged 8-15 with persistent post-concussion syndrome.

What They Found

Following 60 daily sessions, the HBOT group (n=15) showed significant improvements in cognitive function, including general cognitive score (d=0.598, p=0.01) and executive function (d=0.739, p=0.003), compared to the sham group (n=10). They also experienced better emotional scores (p=0.04) and reduced hyperactivity (d=0.244, p=0.03), with clinical outcomes correlating with positive brain MRI changes.

What This Means for Canadian Patients

This therapy could offer a new treatment option for Canadian children suffering from long-term post-concussion symptoms, potentially improving their cognitive abilities and daily behavior. Such improvements could significantly enhance their quality of life and functional independence.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A limitation of this study is its relatively small sample size, which may affect the generalizability of the findings.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 36151105
Year Published 2022
Journal Sci Rep
MeSH Terms Adolescent; Child; Humans; Brain Concussion; Cognition; Hyperbaric Oxygenation; Post-Concussion Syndrome; Quality of Life

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.