What Researchers Did
Researchers investigated whether hyperbaric oxygen therapy could treat systemic inflammatory response syndrome (SIRS) caused by ischaemia-reperfusion injury (IRI) following hand replantation and assessed long-term hand function in two patients.
What They Found
Two male patients in their twenties underwent hand replantation after severe injuries and subsequently developed SIRS. Both patients received three consecutive 90-minute hyperbaric oxygen therapy (HBOT) sessions at 2.4 ATA over three days. After HBOT, both patients showed significant improvement in vital signs and laboratory results, with long-term follow-up up to five years indicating satisfying hand function based on low DASH (Disabilities of the Arm, Shoulder, and Hand) scores.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
As a case report involving only two patients, the findings of this study cannot be generalized to a larger population.